EXAM—Ex vivo allograft monitoring

Analysis of machine perfusion data in kidney transplantation.

Autor:in

Swisstransplant

Veröffentlichungsdatum

19. Dezember 2024

What is EXAM?

EXAM is a dashboard for analyzing hypothermic machine perfusion data from the ORS LifePort Kidney Transporter. EXAM is free software written in the R programming language.

Why is EXAM useful?

EXAM will enable transplant organizations to analyze their data, perform statistics, and conduct quality checks, allowing them to identify potential issues and optimize machine perfusion processes, ultimately benefiting kidney recipients.

Who created EXAM?

EXAM was developed by Swisstransplant—the Swiss national foundation for organ donation and transplantation, in collaboration with three Swiss transplant centers.

Terms of use

By accessing or using this program, you agree to the terms of the GNU Affero General Public License and the following supplements to its sections 15 and 16:

  • The program is provided “as is” without warranty or any obligation from Swisstransplant;
  • Swisstransplant excludes liability for damages, losses, or claims arising from program use, to the extent permitted by law; and
  • You are solely responsible for evaluating the program’s functionality, suitability, and safety before use.

Hypothermic machine perfusion data should not be used as a basis for discarding a kidney allograft.

Please refrain from uploading personal, sensitive, or patient-identifiable data. All uploaded data is temporary and will be automatically deleted at the end of the session. The developers assume no liability for any misuse of the application or the data provided by users.

Dashboard

Here is the link to the EXAM dashboard. The EXAM source code is maintained on GitHub.

Research and data analysis

For research purposes, LifePort data can be loaded and analyzed using the Swisstransplant R package swt. A showcase is provided here https://data.swisstransplant.org/lifeport/.

References

Schwab S, Steck H, Binet I, Elmer A, Ender W, Franscini N, Haidar F, Kuhn C, Sidler D, Storni F, Krügel N, Immer F. EXAM: Ex-vivo allograft monitoring dashboard for the analysis of hypothermic machine perfusion data in deceased-donor kidney transplantation. PLOS Digit Health. 2024;3(12):e0000691. doi:10.1371/journal.pdig.0000691

Schwab S. EXAM: Ex Vivo Allograft Monitoring Dashboard. Github; 2025. Accessed February 13, 2025. https://github.com/Swisstransplant/EXAM

Schwab S. swt: Swisstransplant R Package. Github; 2024. Accessed February 13, 2025. https://github.com/Swisstransplant/swt

Acknowledgments

EXAM was developed by Swisstransplant and three Swiss transplant centers.