EXAM—Ex vivo allograft monitoring

Analysis of machine perfusion data in kidney transplantation.

Autor:in

Swisstransplant

Veröffentlichungsdatum

19. Dezember 2024

What is EXAM?

EXAM is a dashboard for analyzing hypothermic machine perfusion data from the ORS LifePort Kidney Transporter. EXAM is free software written in the R programming language.

Why is EXAM useful?

EXAM will enable transplant organizations to analyze their data, perform statistics, and conduct quality checks, allowing them to identify potential issues and optimize machine perfusion processes, ultimately benefiting kidney recipients.

Who created EXAM?

EXAM was developed by Swisstransplant—the Swiss national foundation for organ donation and transplantation, in collaboration with three Swiss transplant centers.

Terms of use

This program is distributed in the hope that it will be useful, but WITHOUT ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU Affero General Public License for more details.

Important

Hypothermic machine perfusion data alone should never be used as the sole basis to discard a kidney allograft.

Please do not upload personal, sensitive, or patient-identifiable data. Any data uploaded to the application is temporary and will be automatically deleted when the session ends. The developers are not liable for any misuse of the application or the data provided by users.

Dashboard

Here is the link to the EXAM dashboard. The EXAM source code is maintained on GitHub. For research purposes, LifePort data can be parsed and processed using the Swisstransplant R package named swt.

References

Schwab S, Steck H, Binet I, Elmer A, Ender W, Franscini N, Haidar F, Kuhn C, Sidler D, Storni F, Krügel N, Immer F. EXAM: Ex-vivo allograft monitoring dashboard for the analysis of hypothermic machine perfusion data in deceased-donor kidney transplantation. PLOS Digit Health. 2024;3(12):e0000691. doi:10.1371/journal.pdig.0000691

Acknowledgments

EXAM was developed by Swisstransplant and three Swiss transplant centers.